Comparison of cervical acid phosphatase papanicolaou stain and standard papanicolaou stain as a screening tool for cancer cervix

Background: Carcinoma cervix is the second most common cancer in women (18%). Cervical smear by routine Papanicolaou (Pap) screening has significant rates of false-positive and false-negative results. To minimise this, we compare efficacy cervical acid phosphatase-papanicolaou (CAP-Pap) with conventional Pap detecting premalignant lesions cervix. The red-colored granules (enzyme coated abnormal cells) that are clearly detected, CAP-Pap positive aids quick early diagnosis aberrant cells, which speeds up procedureMethods: present observational study conducted among patients presenting to gynaecology department for screening. Two smears were collected staining. Cytology report showing abnormality either or subjected colposcopy guided biopsy after VIA/VILI their results correlated histopathology reports as gold standard.Results: Total 321 enrolled study. On comparison biopsy, had a sensitivity 83.3%, specificity 50%, Positive predictive value 88.2%, Negative 40.0%. 100%, PPV 90%, NPV 100%. As evidenced 100% sensitivity, meets test criteria.Conclusions: CAP- bright future rapid, inexpensive, efficient method initial an addition primary health care India effective